This study investigates the types of misinformation spread on Twitter that evokes scientific authority or evidence when making false claims about the antimalarial drug hydroxychloroquine as a treatment for COVID-19. Specifically, we examined tweets generated after former U.S. President Donald Trump retweeted misinformation about the drug using an unsupervised machine learning approach called the biterm topic model that is used to cluster tweets into misinformation topics based on textual similarity. The top 10 tweets from each topic cluster were content coded (...) for three types of misinformation categories related to scientific authority: medical endorsements of hydroxychloroquine, scientific information used to support hydroxychloroquine’s use, and a comparison group that included scientific evidence opposing hydroxychloroquine’s use. Results show a much higher volume of tweets featuring medical endorsements and use of supportive scientific information compared to accurate and updated scientific evidence, that misinformation-related tweets propagated for a longer time frame, and the majority of hydroxychloroquine Twitter discourse expressed positive views about the drug. Metadata from Twitter accounts found that prominent users within misinformation discourse were more likely to have media or political affiliation and explicitly expressed support for President Trump. Conversely, prominent accounts within the scientific opposition discourse primarily consisted of medical doctors or scientists but had far less influence in the Twitter discourse. Implications of these findings and connections to related social media research are discussed, as well as cognitive mechanisms for understanding susceptibility to misinformation and strategies to combat misinformation spread via online platforms. (shrink)

The impact on researchers of working with sensitive data is often not considered by ethics committees when approving research proposals. We conducted interviews with eight research assistants processing clinical notes on emergency department presentations for deliberate self-harm and suicide attempts during a suicide prevention trial. Common experiences of working with the data included feeling unprepared for the level of detail in the records, being drawn deeply into individual stories, emotional exhaustion from the cumulative exposure to the data over long periods (...) of time while working alone, and experiencing a heightened awareness of the fragility of life and the need for safety. The research assistants also reported on some of the strategies they had developed to cope with the sensitive nature of the data and the demands of the work. The ethical implications for suicide research reliant on non-clinically trained researchers exploring sensitive data are considered. These include the need for research l... (shrink)

This paper investigates force shift, a phenomenon in which the canonical discourse conventions, or force, associated with a clause type can be overridden to yield polar questions with the help of additional force-indicating devices. Previous studies attribute force shift to the presence of a complex question force component operating on semantic content. Based on utterance particles and particle clusters in Cantonese, we analyze force shift as resulting from compositional operations on force-bearing expressions. We propose that a simplex force, such as (...) assertion or question, denotes unanchored sentence acts, while a force-shifting particle like Cantonese _ho2_ is an anchoring function anchoring a sentence act to the speaker while querying whether or not the addressee can perform the sentence act. The proposed semantics makes predictions about _ho2_’s interactions with addressee-changing operations and imperatives, as well as about a larger family of force shift phenomena. (shrink)

The purpose of this study was to develop a Physician's Spiritual Well-Being Scale (PSpWBS). The significance of a physician's spiritual well-being was explored through in-depth interviews with and qualitative data collection from focus groups. Based on the results of qualitative analysis and related literature, the PSpWBS consisting of 25 questions was established. Reliability and validity tests were performed on 177 subjects. Four domains of the PSpWBS were devised: physician's characteristics; medical practice challenges; response to changes; and overall well-being. The explainable (...) total variance was 65.65%. Cronbach α was 0.864 when the internal consistency of the whole scale was calculated. Factor analysis showed that the internal consistency Cronbach α value for each factor was between 0.625 and 0.794 and the split-half reliability was 0.865. The scale has satisfactory reliability and validity and could serve as the basis for assessment of the spiritual well-being of a physician. (shrink)

Noise in behavior is often viewed as a nuisance: while the mind aims to take the best possible action, it is let down by unreliability in the sensory and response systems. How researchers study cognition reflects this viewpoint – averaging over trials and participants to discover the deterministic relationships between experimental manipulations and their behavioral consequences, with noise represented as additive, often Gaussian, and independent. Yet a careful look at behavioral noise reveals rich structure that defies easy explanation. First, both (...) perceptual and preferential judgments show that sensory and response noise may potentially only play minor roles, with most noise arising in the cognitive computations. Second, the functional form of the noise is both non-Gaussian and non-independent, with the distribution of noise being better characterized as heavy-tailed and as having substantial long-range autocorrelations. It is possible that this structure results from brains that are, for some reason, bedeviled by a fundamental design flaw, albeit one with intriguingly distinctive characteristics. Alternatively, noise might not be a bug but a feature: indeed, we suggest that noise is fundamental to how cognition works. Specifically, we propose that the brain approximates probabilistic inference with a local sampling algorithm, one that uses randomness to drive its exploration of alternative hypotheses. Reframing cognition in this way explains the rich structure of noise and leads to a surprising conclusion: that noise is not a symptom of cognitive malfunction but plays a central role in underpinning human intelligence. (shrink)

Previous work has shown that memory performance in older adults is affected by activation of a stereotype of age-related memory decline. In the present experiment, we examined whether stereotype threat would affect metamemory in older adults; that is, whether under stereotype threat they make poorer judgments about what they could remember. We tested older adults (MAge= 66.18 years) on a task in which participants viewed words paired with point values and “bet” on whether they could later recall each word. If (...) they bet on and recalled a word, they gained those points, but if they bet on and failed to recall a word, they lost those points. Thus, this task required participants to monitor how much they could remember and prioritize high value items. Participants performed this task over six lists of items either under stereotype threat about age-related memory decline or not under stereotype threat. Participants from both groups performed similarly on initial lists, but on later lists, participants under stereotype threat showed impaired performance as indicated by a lower average point score and a lower average gamma coefficient. The results suggest that a modest effect of stereotype threat on recall combined with a modest effect on metacognitive judgments to result in a performance deficit. This pattern of results may reflect an effect of stereotype threat on executive control reducing the ability to strategically use memory. (shrink)

The groundbreaking, viewpoint theory of Merker et al. explains several properties of the conscious field, including why the observer cannot directly apprehend itself. We propose that viewpoint theory might also provide a progressive, constitutive marker of consciousness and shed light on why most of the contents of consciousness are encapsulated.

Lower plasma levels of high-density lipoproteins in adolescents with type 2 diabetes have been associated with a higher pulse wave velocity, a marker of arterial stiffness. Evidence suggests that HDL proteins or particle subspecies are altered in T2D and these may drive these relationships. In this work, we set out to reveal any specific proteins and subspecies that are related to arterial stiffness in youth with T2D from proteomics data. Plasma and PWV measurements were previously acquired from lean and T2D (...) adolescents. Each plasma sample was separated into 18 fractions and evaluated by mass spectrometry. Then, we applied a validated network-based computational approach to reveal HDL subspecies associated with PWV. Among 68 detected phospholipid-associated proteins, we found that seven were negatively correlated with PWV, indicating that they may be atheroprotective. Conversely, nine proteins show positive correlation with PWV, suggesting that they may be related to arterial stiffness. Intriguingly, our results demonstrate that apoA-I and histidine-rich glycoprotein may reverse their protective roles and become antagonistic in the setting of T2D. Furthermore, we revealed two arterial stiffness-associated HDL subspecies, each of which contains multiple PWV-related proteins. Correlation and disease association analyses suggest that these HDL subspecies might link T2D to its cardiovascular-related complications. (shrink)

COVID-19 often manifests with different outcomes in different patients, highlighting the complexity of the host-pathogen interactions involved in manifestations of the disease at the molecular and cellular levels. In this paper, we propose a set of postulates and a framework for systematically understanding complex molecular host-pathogen interaction networks. Specifically, we first propose four host-pathogen interaction (HPI) postulates as the basis for understanding molecular and cellular host-pathogen interactions and their relations to disease outcomes. These four postulates cover the evolutionary dispositions involved (...) in HPIs, the dynamic nature of HPI outcomes, roles that HPI components may occupy leading to such outcomes, and HPI checkpoints that are critical for specific disease outcomes. Based on these postulates, an HPI Postulate and Ontology (HPIPO) framework is proposed to apply interoperable ontologies to systematically model and represent various granular details and knowledge within the scope of the HPI postulates, in a way that will support AI-ready data standardization, sharing, integration, and analysis. As a demonstration, the HPI postulates and the HPIPO framework were applied to study COVID-19 with the Coronavirus Infectious Disease Ontology (CIDO), leading to a novel approach to rational design of drug/vaccine cocktails aimed at interrupting processes occurring at critical host-coronavirus interaction checkpoints. Furthermore, the host-coronavirus protein-protein interactions (PPIs) relevant to COVID-19 were predicted and evaluated based on prior knowledge of curated PPIs and domain-domain interactions, and how such studies can be further explored with the HPI postulates and the HPIPO framework is discussed. (shrink)

In her anchor-piece on historicizing the canon, Li-Hsiang Lisa Rosenlee appeals to professional philosophers to develop several tools that can be implemented in historicizing the canon. Amy Donahue, David H. Kim, Nelson Maldonado-Torres, and Kris Sealey tessellate different aspects of this call. Donahue augments Rosenlee’s argument by braiding together Dharmakīrti’s “anyāpoha” theory and Charles Mills’ ruminations about “white ignorance”; Kim explores some of the nuances of Rosenlee’s account for a post-Eurocentric philosophy; Maldonado-Torres ruminates about the larger social context in which (...) thinking can be decolonized; and Sealey uses the work of Kristie Dotson to acknowledge the possibility of multiple canons. In putting on the table a number of questions, concepts, and approaches to canon-building, the symposium aims to contribute to what is by now a large array of similar reflections and engagements in different parts of the world. (shrink)

We conducted the largest multiple-iteration retelling study to date (12,840 participants and 19,086 retellings) with two different studies that test how emotional appraisals are transmitted across retellings. We use a novel Bayesian model that tracks changes across retellings. Study 1 examines the preservation of appraisals of happy and sad stories and finds that retellings preserve the story’s degree of happiness and sadness even when length shrinks and aspects of story coherence and rationalisation deteriorate. Study 2 compared the transmission of appraisals (...) of happiness and sadness with embarrassment, disgust, and risk. Appraisals of happiness, sadness, and also embarrassment showed high appraisal preservation, while disgust and risk were not well preserved. We conclude that participants in our studies encoded happy and sad stories by encapsulating the events and details into an overall emotional appraisal of the story and that this processing strategy might also apply to stories involving other emotions like embarrassment. The emotional appraisal played a key role in retelling by helping to guide the selection, invention, and ordering of the story elements. Hence, we posit that emotion appraisals can operate as anchors for remembering and retelling stories, thus playing an important role in narrative communication. (shrink)

Islamic ethics in the light of Qurʼanic teaching and Hadith; Customs and practices.

One of the problems regarding one of the breaking points in the history of Islamic thought is the presidency. Muslims did not only fall into a theoretical conflict on this issue, but unfortunately, they also engaged in actual battles. The disagreement among Muslims has retained its influence to the present day and has shaped both the religious and worldly views of Muslims. The debate on the identity of the candidate who will assume the role of Muhammad and organize the religious (...) and worldly affairs of Muslims has set the scene of historical conflicts that manifest themselves in the theoretical and practical fields. The religious references made in order to legitimize the political theses caused the said theses to be institutionalized, and matters basically of a political character were associated with religion. Among the Islamic sects, especially Shia, attributed an existential meaning to the problem of the presidency and shaped all their religious and worldly views on this axis. The Shia, who considered the presidency almost a basis of faith, assigned a rank close to prophethood to the heads of state. Zaydiyya stands out as the closest branch of the Shia to the Ahl al-Sunnah in terms of politics. They think more moderately about the characteristics of the head of state, heads of state other than Ali, and the Companions. Ahl as-Sunnah considers the presidency essentially as a juristically -political issue. Bringing this discussion into the field of belief, even with the aim of objecting to Shia, who sees the presidency as a problem of faith and systematizes this problem, shows the first effects of Shia on Sunni political thought. In order to defend Ali's presidency and to question the legitimacy of others, Shia brought the issue into the field of belief, and sought to prove that Ali was superior in the sight of Allah, and therefore, more worthy of the presidency, by referring to various religious texts. Shia examined the issue in a dogmatic way in order to prove his political theses strongly and establish absolute authority. As an inevitable consequence of this method, the institution of the presidency is endowed with divine powers. The theses that the heads of state are appointed with religious references and have the quality of ismah (infallibility) are the most concrete reflections of this approach. Ahl as-Sunnah tried to justify Abu Bakr's legitimacy by defending his superiority against Shia, who defended Ali's superiority. This approach reveals the methodical interaction as well as taking on the mission of responding to Shia effectively in its own way. Shamsaddin as-Samarqandī, whose political imagination we have examined, is a Sunni scholar belonging to the Hanafi - Maturidite kalam tradition. Due to his political views and style, he is also described as a Shiite by some. By examining Samarqandī's concept of politics in the context of his ideas on the general philosophy of theology, we can have clearer information about his sectarian belonging and political stance. He adopted the analytical method in politics, as in other issues, and revealed his own unique style and views, while adhering to the main vein of Ahl as-Sunnah. He adopted the analytical method in politics, as in other issues, and revealed his own unique style and views, while adhering to the main street of Ahl al-Sunnah. (shrink)

Since the beginning of human history, there has been no society that did not have any religion. Man meets his need to believe, encoded in his nature by turning to God. God has not left humans alone in their journey on earth, and from time to time, He has intervened in the world through his prophets. The prophethood, which constitutes one of the main subjects of theology, is an important institution in God-human communication. The messengers chosen by God convey to (...) people the information that they received through revelation and offer teachings that will bring them to salvation. The idea of salvation by God when suffering or feeling helpless has driven people to the expectation of a savior. Nearly all religions except Shintoism have the awaited savior belief in the world. Accordingly, the savior will emerge in an environment of chaos where disasters are experienced, and a moral collapse is observed. The expected savior will drive people away from this turmoil, bring them happiness, well-being, and lead them to salvation. Although there is a savior belief in Judaism and Christianity, Muslims claim that the awaited savior in these religions is Muhammad. Muslim thinkers who believe that Muhammad was heralded in previous scripts, tried to find evidence on the subject from the Bible. One of the Islamic scholars who did researches for this purpose is Shamsuddin al-Samarqandi. Shamsuddin Mohammed b. Ashraf al-Husayni al-Samarqandi is an important Turkish-Islamic scholar who lived in Turkestan at the end of the 7th century and the first quarter of the 8th century. Samarqandi is a versatile scholar who produced important works in various fields such as philosophy, logic, mathematics, discussion, debate and astronomy. Shamsuddin al-Samarqandi is one of the eminent scholars who have written his name in the history of science and philosophy with his works. He adopted a critical and analytical style in almost every field, putting the science of logic at the center of his system. His constructive criticisms had an important function in understanding and interpreting the ideas of numerous thinkers, from Greek philosophers to Islamic philosophers and representatives of philosophical theology. In addition to all these, Samarqandi did not hesitate to criticize the Christian and Jewish belief systems, religions such as Sanawiyyah and Zoroastrianism, and the teachings of the naturalist philosophers regarding the relationship between God and the world in the light of rational and scriptural evidence. Samarqandi, who distinguished himself in rational sciences, also showed himself with his background in theology. Due to his exceptional intellectual interest, he analyzes some key concepts and divine codes related to the Bible, making original inferences about the loyalty of Muhammad, the prophet of Islam. Samarqandi interprets some passages of the Torah and the New Testament, which he considers as signs of Muhammad's prophethood, in the axis of language, logic and the rules of shariah, and concludes that Muhammad is the last prophet to be announced. The conceptual framework that he mostly focuses on in this regard contains Mount Paran, Paraklite, comparison with Moses, and the good news given to the Ishmaelites. Samarqandi makes inferences about the environment in which Muhammad appeared, his qualities, and his lineage, based on the aforementioned concepts. Samarqandi also responds to the criticisms raised by the Ahl al-Kitab about the principles, such as the abolition of other religious rules constituting the basis of Muhammad's legitimacy and establishment of Islam instead, and him being a universal prophet. An important privilege of Samarqandi is that he not only grounds his claims on a theoretical scale but also engages in debates with the leaders of the Ahl al-Kitab. Although Samarqandi exhibits a satisfactory analytical attitude in most of his claims, he displays a sophisticated approach based on the method of coercion (ilzām) in some of his claims. Although he adheres to the tradition of beshair al-nubuwwah in general, he gives a different perspective and strong reasoning to the same evidence within the tradition with the effect of his identity as a verifier (muhaqqik). (shrink)

The Shams al-dīn al-Samarqandī who is the first scholar to adopt the method of the philosophical theology in the Hanafī-Māturīdī tradition, is an important Turkish-Islamic thinker who has proven himself in rational and transmitted sciences by giving works in various fields such as theology, logic, mathematics, astronomy, tafsir, ādāb al-bahth wa al-munāzara. Placing the science of logic at the center of his system, al-Samarqandī analyzed every opinion and evidence put forward logically and aimed to reach the truth. Divine attributes, the (...) temporality of the universe, and the God-universe relationship are at the forefront of the subjects that he aims to reach certain and real knowledge. In this respect, al-Samarqandī analyzed the ontological character of divine and universal attributes. The concept of the hypothetical existential essence plays a key role for the author, who begins by analyzing the types of quiddity. defining the concept of existential as As “that which is without any negativity in its essence and truth", al-Samarqandī, who stipulates to exist as a block and not to have any negativity in its existence, brings a unique expansion to this concept. al-Samarqandī, who defines determination as "an adjective that distinguishes the existent from all mental and external beings", claims that this concept has an existential essence. As a result of his concerns about necesarry existence, Samarqandi, who does not deny the philosophers who accept the necessary existence and determination as identical, also overcomes the problems of multiplicity and causality that may arise about God, with the concept of "hypothetical", if he considers determination as "existential". As a matter of fact, al-Samarqandī divides existence into two parts as real and hypothetical, and defines the real existence as "existing in the real sense and not based on any rational assumption"; defines hypothetical existence as "based on rational assumption". In this case, it is not possible to talk about a real multiplicity or causality. al-Samarqandī claims that the concept of necessity falls within the scope of the hypothetical existential essence. Because wujûb means “the essence necessarily necessitates existence”. It is deduced that wujûb must also be existential, since something necessitating existence must take the judgment of existence. By characterizing the concept of wujûb with hypothetical essence, in the sense of a mental formation that is immune to objective existence, he also avoids the doubt of plurality. Concerned that the regard of possibility as an existential essence may require God to be necessary per se and the universe to be eternal, theologians accepted possibility as an absent essence. al-Samarqandī states that possibility can be accepted within the scope of true non-existent or hypothetical existential essence. As a matter of fact, evaluating the possibility in this way also eliminates the possibility that God is necessary and the universe is ancient. Attributes that can be attributed to God and can create a multiplicity in His essence or that can be attributed to the universe and cause the universe to be eternal are evaluated within the scope of the concept of the hypothetical existential essence, and, the idea that God is unique and that he is the only eternal entity is based on this concept. (shrink)

We review state‐of‐the‐art computational methods for constructing, from image data, generative statistical models of cellular and nuclear shapes and the arrangement of subcellular structures and proteins within them. These automated approaches allow consistent analysis of images of cells for the purposes of learning the range of possible phenotypes, discriminating between them, and informing further investigation. Such models can also provide realistic geometry and initial protein locations to simulations in order to better understand cellular and subcellular processes. To determine the structures (...) of cellular components and how proteins and other molecules are distributed among them, the generative modeling approach described here can be coupled with high throughput imaging technology to infer and represent subcellular organization from data with few a priori assumptions. We also discuss potential improvements to these methods and future directions for research. (shrink)

Monetary intelligence theory asserts that individuals apply their money attitude to frame critical concerns in the context and strategically select certain options to achieve financial goals and ultimate happiness. This study explores the dark side of monetary Intelligence and behavioral economics—dishonesty. Dishonesty, a risky prospect, involves cost–benefit analysis of self-interest. We frame good or bad barrels in the environmental context as a proxy of high or low probability of getting caught for dishonesty, respectively. We theorize: The magnitude and intensity of (...) the relationship between love of money and dishonest prospect may reveal how individuals frame dishonesty in the context of two levels of subjective norm—perceived corporate ethical values at the micro-level and Corruption Perceptions Index at the macro-level, collected from multiple sources. Based on 6382 managers in 31 geopolitical entities across six continents, our cross-level three-way interaction effect illustrates: As expected, managers in good barrels, mixed barrels, and bad barrels display low, medium, and high magnitude of dishonesty, respectively. With high CEV, the intensity is the same across cultures. With low CEV, the intensity of dishonesty is the highest in high CPI entities —the Enron Effect, but the lowest in low CPI entities. CPI has a strong impact on the magnitude of dishonesty, whereas CEV has a strong impact on the intensity of dishonesty. We demonstrate dishonesty in light of monetary values and two frames of social norm, revealing critical implications to the field of behavioral economics and business ethics. (shrink)

In Beck, focus intervention is used as an argument for reducing Hamblin’s semantics for questions to Rooth’s focus semantics. Drawing on novel empirical evidence from Mandarin and English, we argue that this reduction is unwarranted. Maintaining both Hamblin’s original semantics and Rooth’s focus semantics not only allows for a more adequate account for focus intervention in questions, but also correctly predicts that focus intervention is a very general phenomenon caused by interaction of alternatives in different dimensions.

The target article argues researchers should be more ambitious, designing studies that systematically and comprehensively explore the space of possible experiments in one fell swoop. We argue that while “systematic” is rarely achievable, “comprehensive” is often enough. Critically, the recent popularization of massive online experiments shows that comprehensive studies are achievable for most cognitive and behavioral research questions.

Corruption involves greed, money, and risky decision-making. We explore the love of money, pay satisfaction, probability of risk, and dishonesty across cultures. Avaricious monetary aspiration breeds unethicality. Prospect theory frames decisions in the gains-losses domain and high-low probability. Pay dissatisfaction (in the losses domain) incites dishonesty in the name of justice at the individual level. The Corruption Perceptions Index, CPI, signals a high-low probability of getting caught for dishonesty at the country level. We theorize that decision-makers adopt avaricious love-of-money aspiration (...) as a lens and frame dishonesty in the gains-losses domain (pay satisfaction-dissatisfaction, Level 1) and high-low probability (CPI, Level 2) to maximize expected utility and ultimate serenity. We challenge the myth: Pay satisfaction mitigates dishonesty across nations consistently. Based on 6500 managers in 32 countries, our cross-level three-dimensional visualization offers the following discoveries. Under high aspiration conditions, pay dissatisfaction excites the highest- (third-highest) avaricious justice-seeking dishonesty in high (medium) CPI nations, supporting the certainty effect. However, pay satisfaction provokes the second-highest avaricious opportunity-seizing dishonesty in low CPI entities, sustaining the possibility effect—maximizing expected utility. Under low aspiration conditions, high pay satisfaction consistently leads to low dishonesty, demonstrating risk aversion—achieving ultimate serenity. We expand prospect theory from a micro and individual-level theory to a cross-level theory of monetary wisdom across 32 nations. We enhance the S-shaped Curve to three 3-D corruption surfaces across three levels of the global economic pyramid, providing novel insights into behavioral economics, business ethics, the environment, and responsibility. (shrink)

Emerging adult newlywed couples often experience many demands on their time, and three common problems may surface as couples try to balance these demands—problems related to finances, sleep, and sex. We used two waves of dyadic data from 1,001 emerging adult newlywed couples to identify four dyadic latent profiles from husbands’ and wives’ financial management behaviors, sexual satisfaction, and sleep quality: Flounderers, Financially Challenged Lovers, Drowsy Budgeters, and Flourishers. We then examined how husbands’ and wives’ marital satisfaction, in relation to (...) profile membership, varied at a later wave. We found that Financially Challenged Lovers and Flourishers had significantly higher marital satisfaction than Drowsy Budgeters and Flounderers. Whereas, Financially Challenged Lovers and Flourishers did not differ in terms of marital satisfaction, Drowsy Budgeters seemed to have slightly higher marital satisfaction than Flounderers for wives only. However, we did not find evidence that these connections meaningfully differed by sex. Implications for the efforts of clinicians and educators are discussed. (shrink)

Adaptation to climate change impacts is a key research topic in business ethics that poses substantial implications on the good lives of human beings. The commercial port sector is a highly relevant study focus with its pivotal roles in supply chains and international trade. Hence, it is important to investigate whether the port planning system and practice is appropriate in tackling climate change impacts. But beforehand, we must thoroughly understand the attitude and behaviors of port planners and operators on ports’ (...) climate adaptation planning. Through a survey towards 21 ports in Canada, the paper investigates the attitude and behaviors of port planners and operators on ports’ climate adaptation planning. Towards the end, we propose a new approach so as to enable port stakeholders to carry out climate adaptation planning effectively. The paper offers important insight to researchers to investigate the ways in developing effective climate adaptation plans and practice for ports and other business sectors. (shrink)

PurposeThis study aims to develop and validate a stigma scale for Chinese patients with breast cancer.MethodsPatients admitted to the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, for breast cancer treatment participated in this study. Development of the Breast Cancer Stigma Scale involved the following procedures: literature review, interview, and applying a theoretical model to generate items; the Breast Cancer Stigma Scale’s content validity was assessed by a Delphi study and feedback from patients with breast cancer ; (...) exploratory factor analysis was used to assess the construct validity; convergent validity was assessed with the Social Impact Scale ; internal consistency Cronbach’s α, split-half reliability, and test–retest reliability were used to identify the reliability of the scale.ResultsThe final version of the Breast Cancer Stigma Scale consisted of 15 items and showed positive correlations with the Social Impact Scale. Exploratory factor analysis revealed four components of the Breast Cancer Stigma Scale: self-image impairment, social isolation, discrimination, and internalized stigma, which were strongly related to our perceived breast cancer stigma model and accounted for 69.443% of the total variance. Cronbach’s α for the total scale was 0.86, and each subscale was 0.75–0.882. The test–retest reliability with intra-class correlation coefficients of the total scale was 0.947, and split-half reliability with intra-class correlation coefficients of the total scale was 0.911. The content validity index was 0.73–1.0.ConclusionThe newly developed Breast Cancer Stigma Scale offers a valid and reliable instrument for assessing the perceived stigma of patients with breast cancer in clinical and research settings. It may be helpful for stigma prevention in China. (shrink)

DBS Think Tank IX was held on August 25–27, 2021 in Orlando FL with US based participants largely in person and overseas participants joining by video conferencing technology. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers and researchers can freely discuss current and emerging deep brain stimulation technologies as well as the logistical and ethical issues facing the field. The consensus among the DBS Think Tank IX speakers was that DBS expanded in (...) its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. After collectively sharing our experiences, it was estimated that globally more than 230,000 DBS devices have been implanted for neurological and neuropsychiatric disorders. As such, this year’s meeting was focused on advances in the following areas: neuromodulation in Europe, Asia and Australia; cutting-edge technologies, neuroethics, interventional psychiatry, adaptive DBS, neuromodulation for pain, network neuromodulation for epilepsy and neuromodulation for traumatic brain injury. (shrink)

The purpose of this research is to investigate the effectiveness of Digital Content Marketing on a Mixed Reality training platform environment with the consideration of online purchase intention through social media. E-commerce today encounters several common issues that cause customers to have reservations to purchase online. With the absence of physical contact points, customers often perceive more risks when making purchase decisions. Furthermore, online retailers often find it hard to engage customers and develop long-term relationships. In this research, a Structural (...) Equation Model is proposed to examine the efficacy of DCM from both immediate and long-term OPI. The results examine whether adopting DCM on an MR training platform environment through social media brings positive results in OPI. Empirical research was carried out through online questionnaires collected in 2021 and 2022. A total of 374 questionnaires were qualified for data analysis in this study, conducted with IBM SPSS and AMOS. The results imply that DCM is critical to stimulating both immediate and long-term OPI. The immediate OPI is positively affected by increasing perceived value through MR in DCM. Regarding the long-term OPI, increased customer engagement with DCM under MR environment can cultivate brand trust and significantly affect the long-term OPI. (shrink)